HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → HCID 68183325, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | HCID 68183108 | HCID 68183108 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 68183325 | HCID 68183325 | 72% |
Reaction Steps
In a similar fashion using route 1 general procedure 4,5,6-difluoro-8-nitroquinoline (Intermediate 37) (200 mg, 0.95 mmol), tin (II) chloride (540 mg, 2.85 mmol) and 6N HCl (2 drops) gave the title compound (120 mg, 72%) which was used in the next step without purification. The structure was confirmed by 1H NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-04ea7484e7f14c2c910200aed925b114 |
| Source note | uspto-grants-2015_08 |