HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzenesulfonyl chloride, 2,4-dichloro- → 2,4-Dichloro-N-(5-chloro-quinolin-8-yl)-benzenesulfonamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzenesulfonyl chloride, 2,4-dichloro- | HCID 204419 | — |
| Edukt | 5-Chloroquinolin-8-amine | HCID 224860 | — |
| Produkt | 2,4-Dichloro-N-(5-chloro-quinolin-8-yl)-benzenesulfonamide | HCID 68183486 | 40% |
Reaktionsschritte
In a similar fashion using route 14 general procedure 26, 5-chloroquinolin-8-amine (Intermediate 27) (50 mg, 0.28 mmol), 2,4-dichlorobenzenesulfonyl chloride (103 mg, 0.42 mmol) gave the title compound (40 mg, 40%) after purification by column chromatography with DCM as the eluent.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09102688B2 |
| Quelldatensatz | uspto-grants-2015_08 |
| ORD ID | ord-3081ec9434f84c8883de18e3c4610d4f |
| Quellennotiz | uspto-grants-2015_08 |