反应详情

In a similar fashion using route 14 general procedure 27, 6-ethoxyquinolin-8-amine (Intermediate 47) (150 mg, 0.8 mmol), benzenesulfonyl chloride (170 mg, 0.96 mmol) and DMAP (cat.) gave the title compound (85 mg, 33%) after purification by column chromatography with n-hexane/DCM (1:0-0:1) as the eluent and recrystallisation from DCM/n-pentane.