反应详情

In a similar fashion using route 14 general procedure 27, 6-fluoroquinolin-8-amine (Intermediate 48) (60 mg, 0.37 mmol), benzenesulfonyl chloride (78 mg, 0.44 mmol) and DMAP (cat.) gave the title compound (40 mg, 36%) after purification by column chromatography with DCM as the eluent.