反应详情

In a similar fashion using route 14 general procedure 27, 8-aminoqunoline (40 mg, 0.27 mmol), 5-methyl-pyridine-2-sulfonyl chloride 440 (79 mg, 0.41 mmol), pyridine (1.5 ml) DMAP (cat.) and DCM (2 ml) gave the title compound (21 mg, 25%) after purification by column chromatography with n-hexane/EtOAc (93:7) as the eluent.