反应详情

In a similar fashion using route 14 general procedure 26, 5-chloro-8-aminoquinoline (Intermediate 27) (150 mg, 0.84 mmol), 2-nitro-4-methylbenzenesulfonyl chloride (Intermediate 20) (228 mg, 1.26 mmol) gave the title compound (170 mg, 54%) after purification by column chromatography with DCM as the eluent.