HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitrobenzenesulfonyl chloride → N-(5-methylquinolin-8-yl)-2-nitrobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitrobenzenesulfonyl chloride | HCID 15540 | — |
| Reactant | 5-Methylquinolin-8-amine | HCID 12846625 | — |
| Product | N-(5-methylquinolin-8-yl)-2-nitrobenzenesulfonamide | HCID 68183358 | 57% |
Reaction Steps
In a similar fashion using route 14 general procedure 27, 5-methylquinolin-8-amine (Intermediate 44) (690 mg, 4.38 mmol) and 2-nitrobenzenesulfonyl chloride (1.15 g, 5.24 mmol) gave the title compound (820 mg, 57%). The structure was confirmed by 1H NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-38a842afdeef4dfaa860271cd7a893e3 |
| Source note | uspto-grants-2015_08 |