反应详情

In a similar fashion using route 1 general procedure 4, 2-nitro-N-(5-trifluoromethyl-quinolin-8-yl)-benzenesulfonamide (Intermediate 253) (275 mg, 0.69 mmol), SnCl2 (526 mg, 3.46 mmol), conc.HCl (5 drops) and EtOH (10 ml) gave the title compound (230 mg, 90%) which was used in the next step without further purification.