反应详情

In a similar fashion using route 1 general procedure 4, N-(5-chloro-quinolin-8-yl)-2-nitro-4-trifluoromethyl-benzenesulfonamide (Intermediate 272) (0.7 g, 1.62 mmol), SnCl2 (0.92 g, 4.86 mmol) and EtOH (15 ml) gave the title compound (0.6 g, 92%) which was used in the next step without further purification.