HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Fluoro-5-methyl-2-nitro-benzenesulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Fluoro-5-methyl-2-nitro-benzenesulfonic acid | HCID 86669766 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Fluoro-5-methyl-2-nitro-benzenesulfonyl chloride | HCID 86669759 | 99% |
Reaction Steps
In a similar fashion using route 39 general procedure 96, 4-fluoro-5-methyl-2-nitro-benzenesulfonic acid 452 (1.5 g, 6.38 mmol), SOCl2 (15 ml) and DMF (0.1 ml) gave the title compound (1.6 g, 99%) which was used in the next step without purification. The structure was confirmed by 1H NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-8d19ad974d684069bb0e3c158cd4c4b5 |
| Source note | uspto-grants-2015_08 |