反应详情

In a similar fashion using route 39 general procedure 96, 4-fluoro-5-methyl-2-nitro-benzenesulfonic acid 452 (1.5 g, 6.38 mmol), SOCl2 (15 ml) and DMF (0.1 ml) gave the title compound (1.6 g, 99%) which was used in the next step without purification. The structure was confirmed by 1H NMR.