HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 6,6-Dioxo-5,6-dihydro-6lambda*6*-thia-4,5-diaza-chrysen-1-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 1-Chloro-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide | HCID 68183355 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6,6-Dioxo-5,6-dihydro-6lambda*6*-thia-4,5-diaza-chrysen-1-ylamine | HCID 68190282 | 20% |
Reaction Steps
In a similar fashion using route 48 general procedure 114, 1-chloro-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide 305 (90 mg, 0.28 mmol), 7M NH3 in MeOH (5 ml) gave the title compound (17 mg, 20%) after purification by column chromatography eluting with chloroform/MeOH (98:2:1 drop NH3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-b9df613ad6f84ddf8dc1c0d2dddf6181 |
| Source note | uspto-grants-2015_08 |