反应详情

In a similar fashion using route 51 general procedure 118, 12-chloro-9-fluoro-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide 503 (100 mg, 0.3 mmol), morpholine (0.052 ml, 0.6 mmol) and NMP (2 ml) gave title compound (50 mg, 41%) after purification by column chromatography using chloroform/MeOH (99.5:0.5) as the eluent.