Methylamine → HCID 68190286, compound

Participants

Reaction Steps

In a similar fashion using route 53 general procedure 122,6,6-dioxo-5,6-dihydro-6λ*6*-thia-4,5-diaza-chrysene-9-carboxylic acid methyl ester 307 (20 mg, 0.058 mmol), methylamine (33% in EtOH; 4 ml, 0.58 mmol) at 100° C. gave the title compound (16 mg 84%) after purification by column chromatography with DCM/MeOH (99:1) as the eluent.

Provenance & Evidence