HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 68190302, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 68190303 | HCID 68190303 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68190302 | HCID 68190302 | 93.2% |
Reaction Steps
In a similar fashion using route 53 general procedure 121, 12-chloro-6,6-dioxo-5,6-dihydro-6λ*6*-thia-4,5-diaza-chrysene-9-carboxylic acid methyl ester 523 (0.85 g, 2.2 mmol), LiOH (190 mg, 4.5 mmol), MeOH:H2O:THF (10 ml: 3 ml: 2 ml) gave the title compound (0.74 g, 89%) after washing with MeOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-af64f57b4eed4653a74ea143c61c6193 |
| Source note | uspto-grants-2015_08 |