HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 68183373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 68183202 | HCID 68183202 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68183373 | HCID 68183373 | 50% |
Reaction Steps
In a similar fashion using route 53 general procedure 122, 8-benzenesulfonylamino-quinoline-4-carboxylic acid methyl ester 225 (25 mg, 0.073 mmol) and NH3 in MeOH (7M; 3 ml) gave the title compound (13 mg, 50%) after purification by recrystallisation from DCM.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-161375a6f78d47e4a4e64593c2d3dd25 |
| Source note | uspto-grants-2015_08 |