反应详情

In a similar fashion using route 18 general procedure 26, 8-amino-7-chloro-4-methoxyquinoline 70 (550 mg, 2.6 mmol), 2-nitrobenzenesulphonylchloride (642 mg, 2.9 mmol) in pyridine (10 ml) gave the title compound (580 mg, 55%) which was used in the next step without further purification.