反应详情

In a similar fashion using route 19 general procedure 29, N-(7-chloro-4-methoxy-quinolin-8-yl)-2-nitro-benzenesulfonamide 569 (580 mg, 1.4 mmol), SnCl2 (1.66 g, 7.3 mmol) in EtOH (20 ml) gave the title compound (470 mg, 92%) which was used in the next step without further purification.