HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 2-Amino-N-(7-chloro-4-methoxy-quinolin-8-yl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | N-(7-Chloro-4-methoxy-quinolin-8-yl)-2-nitro-benzenesulfonamide | HCID 68183070 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-N-(7-chloro-4-methoxy-quinolin-8-yl)-benzenesulfonamide | HCID 68183053 | 92.3% |
Reaction Steps
In a similar fashion using route 19 general procedure 29, N-(7-chloro-4-methoxy-quinolin-8-yl)-2-nitro-benzenesulfonamide 569 (580 mg, 1.4 mmol), SnCl2 (1.66 g, 7.3 mmol) in EtOH (20 ml) gave the title compound (470 mg, 92%) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-b4d58d1aecf6403b97da0de248fd20cd |
| Source note | uspto-grants-2015_08 |