HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 4-(2-Methoxyphenyl)-3-methylbutyryl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-(2-Methoxyphenyl)-3-methylbutanoic acid | HCID 23939404 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(2-Methoxyphenyl)-3-methylbutyryl chloride | HCID 86691538 | — |
Reaction Steps
To a solution of 4-(2-methoxyphenyl)-3-methylbutyric acid (24 mmol, crude from previous reaction) in dichloromethane (36 mL) was added oxalyl chloride (2 M in DCM, 36 mL). The reaction was stirred for 1 h at room temperature. All volatiles were removed in vacuo and the crude residue used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102614B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-674f7839d1534e75a175977f3c353d41 |
| Source note | uspto-grants-2015_08 |