HRID514129

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1c(C(OC(C)(C)C)C(=O)O)c(-c2ccc(Cl)cc2)c2ccccc2c1C#CCN(C)C

HCID67126165

未命名化合物

结构：CCc1c(C)c(C(OC(C)(C)C)C(=O)O)c(-c2ccc(Cl)cc2)c2ccccc12

HCID67126286

未命名化合物

PRODUCTS

生成物

HCID67126211

未命名化合物

PROCEDURE

实验过程

2-tert-butoxy-2-(1-(4-chlorophenyl)-4-(3-(dimethylamino)propyl)-3-methylnaphthalen-2-yl)acetic acid (132) was prepared in a manner similar to 2-tert-butoxy-2-(1-(4-chlorophenyl)-4-ethyl-3-methylnaphthalen-2-yl)acetic acid of Example 127, except using 2-tert-butoxy-2-(1-(4-chlorophenyl)-4-(3-(dimethylamino)prop-1-ynyl)-3-methylnaphthalen-2-yl)acetic acid. LCMS-ESI+ (m/z): [M+H]+ calcd for C28H35ClNO3: 468.2; Found: 468.2.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-02cceb2e59d541b69f6202162beb77c4
来源数据集: uspto-grants-2015_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09102614B2
来源说明: uspto-grants-2015_08

反应 SMILES

C(OC(C1C(C)=C(CC)C2C(=CC=CC=2)C=1C1C=CC(Cl)=CC=1)C(O)=O)(C)(C)C.[C:30]([O:34][CH:35]([C:39]1[C:48]([CH3:49])=[C:47]([C:50]#[C:51][CH2:52][N:53]([CH3:55])[CH3:54])[C:46]2[C:41](=[CH:42][CH:43]=[CH:44][CH:45]=2)[C:40]=1[C:56]1[CH:61]=[CH:60][C:59]([Cl:62])=[CH:58][CH:57]=1)[C:36]([OH:38])=[O:37])([CH3:33])([CH3:32])[CH3:31]>>[C:30]([O:34][CH:35]([C:39]1[C:48]([CH3:49])=[C:47]([CH2:50][CH2:51][CH2:52][N:53]([CH3:54])[CH3:55])[C:46]2[C:41](=[CH:42][CH:43]=[CH:44][CH:45]=2)[C:40]=1[C:56]1[CH:57]=[CH:58][C:59]([Cl:62])=[CH:60][CH:61]=1)[C:36]([OH:38])=[O:37])([CH3:33])([CH3:31])[CH3:32]