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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 514129Generated: October 29, 2026

2-Tert-butoxy-2-(1-(4-chlorophenyl)-4-(3-(dimethylamino)prop-1-ynyl)-3-methylnaphthalen-2-yl)acetic acid → 2-Tert-butoxy-2-(1-(4-chlorophenyl)-4-(3-(dimethylamino)propyl)-3-methylnaphthalen-2-yl)acetic acid

https://huagongshe.com/reaction/514129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Tert-butoxy-2-(1-(4-chlorophenyl)-4-(3-(dimethylamino)prop-1-ynyl)-3-methylnaphthalen-2-yl)acetic acidHCID 67126165—
Reactant2-Tert-butoxy-2-(1-(4-chlorophenyl)-4-ethyl-3-methylnaphthalen-2-yl)acetic acidHCID 67126286—
Product2-Tert-butoxy-2-(1-(4-chlorophenyl)-4-(3-(dimethylamino)propyl)-3-methylnaphthalen-2-yl)acetic acidHCID 67126211—

Reaction Steps

2-tert-butoxy-2-(1-(4-chlorophenyl)-4-(3-(dimethylamino)propyl)-3-methylnaphthalen-2-yl)acetic acid (132) was prepared in a manner similar to 2-tert-butoxy-2-(1-(4-chlorophenyl)-4-ethyl-3-methylnaphthalen-2-yl)acetic acid of Example 127, except using 2-tert-butoxy-2-(1-(4-chlorophenyl)-4-(3-(dimethylamino)prop-1-ynyl)-3-methylnaphthalen-2-yl)acetic acid. LCMS-ESI+ (m/z): [M+H]+ calcd for C28H35ClNO3: 468.2; Found: 468.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102614B2
Source datasetuspto-grants-2015_08
ORD IDord-02cceb2e59d541b69f6202162beb77c4
Source noteuspto-grants-2015_08