Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 514578Generated: October 27, 2026

1-(p-Chlorophenyl)cyclopropanecarboxylic acid → HCID 86725681, compound

https://huagongshe.com/reaction/514578

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(p-Chlorophenyl)cyclopropanecarboxylic acidHCID 98606—
ReactantPotassium methyl malonateHCID 2724687—
ProductHCID 86725681HCID 8672568178%

Reaction Steps

The title compound was prepared in 78% yield from 1-(4-chlorophenyl)cyclopropane-1-carboxylic acid and 3-methoxy-3-oxopropanoic acid potassium salt according to the procedure for the preparation of Example 170, part A. 1H NMR (300 MHz, CDCl3): δ 1.22-1.26 (2H, m), 1.70-1.74 (2H, m), 3.35 (2H, s), 3.67 (3H, s), 7.29-7.34 (4H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09107916B2
Source datasetuspto-grants-2015_08
ORD IDord-1b69f5ae26fe456ab10b0dc547848ca9
Source noteuspto-grants-2015_08