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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 514593Generated: October 29, 2026

Water → HCID 58258503, compound

https://huagongshe.com/reaction/514593

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPyrrolidineHCID 31268—
ReactantHCID 58258448HCID 58258448—
ProductHCID 58258503HCID 58258503—

Reaction Steps

A mixture of pyrrolidine (150 ml) and water (15 ml) was stirred at r.t. 1-[[3-chloro-4-(2,2-dibromoethenyl)phenyl]methyl]-pyrrolidine (crude, max. 44.70 mmol) was added to the mixture and subsequently, the mixture was stirred overnight at r.t. The solvent was evaporated, yielding 1-[[2-chloro-4-(1-pyrrolidinylmethyl)phenyl]acetyl]-pyrrolidine as a crude that was used as such in the next reaction step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09107946B2
Source datasetuspto-grants-2015_08
ORD IDord-d4ace16a01b54ee0806cc9dc163f3e3c
Source noteuspto-grants-2015_08