反应详情

A mixture of 3.2 g of N-benzyl-2-hydroxymethyl-4-methoxyindole (12 mmol) and 15 g of manganese dioxide (172 mmol) in 50 cc of dry dichloromethane was heated at reflux for 6 hours, cooled down to r.t. and filtered through celite. Concentration to dryness afford 3.6 g of a yellow solid. mp.130-31° C.

1. temperaturewas heated
2. temperatureat reflux for 6 hours
3. filtrationfiltered through celite
4. concentrationConcentration to dryness