HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 90419711, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 90418937 | HCID 90418937 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 90419711 | HCID 90419711 | — |
Reaction Steps
The solution of tert-butyl-4-(3,3-difluorobutyl)-4-hydroxypiperidine-1-carboxylate (0.932 g, 3.2 mmol) in the solution of HCl in 1,4-dioxane (3M, 5 mL) was stirred at room temperature for 1 hour. The solution was evaporated to dryness under reduced pressure to give the product which was used in the next step without further purification. LC-MS: m/z 194.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09108921B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-0986a5c71fa24906b8485c3312deb837 |
| Source note | uspto-grants-2015_08 |