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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 514840Generated: October 30, 2026

HCID 90419008, compound → HCID 69511460, compound

https://huagongshe.com/reaction/514840

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 90419008HCID 90419008—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 69511460HCID 69511460—

Reaction Steps

A mixture of methyl 2-(difluoromethoxy)-4-nitrobenzoate (330 mg, 1.3 mmol) and 10% Pd on carbon (50 mg) in THF (10 mL) was stirred at room temperature under hydrogen atmosphere for 6 hours. The solid was removed by filtration and the solvent was concentrated to give the crude aniline. LC-MS: m/z 218.1 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09108921B2
Source datasetuspto-grants-2015_08
ORD IDord-7943b2fa7f994862bf244f60857c6a7b
Source noteuspto-grants-2015_08