HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 22736218, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-fluoro-6-{[3-(1H-imidazol-1-yl)propyl]amino}benzonitrile | HCID 2804809 | — |
| Reactant | 4-Amino-7-(3-tetrahydrofuryl)-7H-pyrrolo[2,3-d]pyrimidin-5-ylphenol | HCID 86589004 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22736218 | HCID 22736218 | — |
Reaction Steps
4-[4-Amino-7-(3-tetrahydrofuryl)-7H-pyrrolo[2,3-d]pyrimidin-5-ylphenol (0.49 g), 2-fluoro-6-(3-imidazol-1-yl)propylamino benzonitrile, potassium carbonate (0.45 g) and dimethylformamide were reacted in a similar manner to Example 17 to give 2-[4-(4-amino-7-(3-tetrahydrofuryl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenoxy]-6-(3-imidazol-1-yl)propylaminobenzonitrile, m.p.110° C. (glassy foam).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06713474B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-956daaaca4ca4a3fa766a9628247430b |
| Source note | uspto-grants-2004_03 |