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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 515251Generated: October 30, 2026

Ethyl 2-chloro-1,3-thiazole-5-carboxylate → Ethyl 2-(6-bromo-2-methylpyrimidin-4-ylamino)thiazole-5-formate

https://huagongshe.com/reaction/515251

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chloro-1,3-thiazole-5-carboxylateHCID 19017727—
Reactant4-Amino-6-bromo-2-methylpyrimidineHCID 56965719—
ProductEthyl 2-(6-bromo-2-methylpyrimidin-4-ylamino)thiazole-5-formateHCID 4982180775.5%

Reaction Steps

Prepared from ethyl 2-chlorothiazole-5-formate and Compound 9: ethyl 2-(6-bromo-2-methylpyrimidin-4-ylamino)thiazole-5-formate was yielded (yield: 75.5%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09108954B2
Source datasetuspto-grants-2015_08
ORD IDord-11832d28fa804ee8b6b4032b40e5a2e9
Source noteuspto-grants-2015_08