反应详情

Preparation of 6-(4-[1,2,4]oxadiazol-3-yl-phenyl) -[1,4]oxazepane was performed by the same procedure as that of 5-methyl-[1,4]oxazepane hydrochloride except for utilizing 4-benzyl-6-(4-[1,2,4]oxadiazol-3-yl-phenyl)-[1,4]oxazepane instead of 4-benzyl-5-methyl-[1,4]oxazepane. 6-(4-[1,2,4]Oxadiazol-3-yl-phenyl)-[1,4]oxazepane hydrochloride was obtained as white solid (0.13 g, 0.45 mmol, 86%).