HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzyl-6-(4-[1,2,4]oxadiazol-3-yl-phenyl)-[1,4]oxazepane → 6-(4-[1,2,4]Oxadiazol-3-yl-phenyl)-[1,4]oxazepane hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzyl-6-(4-[1,2,4]oxadiazol-3-yl-phenyl)-[1,4]oxazepane | HCID 66718555 | — |
| Reactant | 5-Methyl-1,4-oxazepane hydrochloride | HCID 66718639 | — |
| Reactant | 6-(4-[1,2,4]Oxadiazol-3-yl-phenyl)-[1,4]oxazepane | HCID 67282209 | — |
| Product | 6-(4-[1,2,4]Oxadiazol-3-yl-phenyl)-[1,4]oxazepane hydrochloride | HCID 67282208 | — |
Reaction Steps
Preparation of 6-(4-[1,2,4]oxadiazol-3-yl-phenyl) -[1,4]oxazepane was performed by the same procedure as that of 5-methyl-[1,4]oxazepane hydrochloride except for utilizing 4-benzyl-6-(4-[1,2,4]oxadiazol-3-yl-phenyl)-[1,4]oxazepane instead of 4-benzyl-5-methyl-[1,4]oxazepane. 6-(4-[1,2,4]Oxadiazol-3-yl-phenyl)-[1,4]oxazepane hydrochloride was obtained as white solid (0.13 g, 0.45 mmol, 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09108957B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-67d329b3dac04e5ea3c5226484f49acc |
| Source note | uspto-grants-2015_08 |