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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 515475Generated: October 30, 2026

7-[4-(5-Methyl-[1,2,4]oxadiazol-3-yl)-phenyl]-[1,4]oxazepane hydrochloride → 6-(4-[1,2,4]Oxadiazol-5-yl-phenyl)-[1,4]oxazepane hydrochloride

https://huagongshe.com/reaction/515475

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-[4-(5-Methyl-[1,2,4]oxadiazol-3-yl)-phenyl]-[1,4]oxazepane hydrochlorideHCID 66718573—
Reactant4-Benzyl-6-(4-[1,2,4]oxadiazol-5-yl-phenyl)-[1,4]oxazepaneHCID 66718595—
Product6-(4-[1,2,4]Oxadiazol-5-yl-phenyl)-[1,4]oxazepane hydrochlorideHCID 67283099—

Reaction Steps

6-(4-[1,2,4]Oxadiazol-5-yl-phenyl)-[1,4]oxazepane hydrochloride was prepared by the same procedure as that of 7-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)-phenyl]-[1,4]oxazepane hydrochloride except for utilizing 4-benzyl-6-(4-[1,2,4]oxadiazol-5-yl-phenyl)-[1,4]oxazepane instead of 7-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)-phenyl]-4-(1-phenyl-ethyl)-[1,4]oxazepane 6-(4-[1,2,4]Oxadiazol-5-yl-phenyl)-[1,4]oxazepane hydrochloride was obtained as white solid (0.03 g, 0.09 mmol, 90%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09108957B2
Source datasetuspto-grants-2015_08
ORD IDord-27494ee2cff64f5081bfc36464a272c5
Source noteuspto-grants-2015_08