HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-N-((4-methoxyphenyl)methyl)-5-(trifluoromethyl)-3-pyridinamine → 3-(Trifluoromethyl)-[2,3'-bipyridin]-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-N-((4-methoxyphenyl)methyl)-5-(trifluoromethyl)-3-pyridinamine | HCID 25020033 | — |
| Reactant | N-(4-methoxybenzyl)-3-(trifluoromethyl)-[2,3'-bipyridin]-5-amine | HCID 67374880 | — |
| Product | 3-(Trifluoromethyl)-[2,3'-bipyridin]-5-amine | HCID 67376011 | — |
Reaction Steps
The title compound was synthesized as described for Intermediate 1, Step 5 using N-(4-methoxybenzyl)-3-(trifluoromethyl)-[2,3′-bipyridin]-5-amine as the starting material. 1H NMR (300 MHz, CDCl3) δ 8.71 (dd, 1H), 8.64 (dd, 1H), 8.30 (dd, 1H), 7.78 (m, 1H), 7.35 (m, 1H), 7.32 (d, 1H), 4.05 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09108944B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-b21b5ff90fb040bd87acd34e3dfae670 |
| Source note | uspto-grants-2015_08 |