Sodium Bicarbonate → HCID 178512158, compound

HRID 515862Notes

Reaction equation

HRID 515862 reaction equation
[Ag+2:1].[CH:2]1[C:7]([NH:8][C:9]([NH:11][C:12]([NH:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][NH:21][C:22]([NH:24][C:25]([NH:27][C:28]2[CH:29]=[CH:30][C:31]([Cl:34])=[CH:32][CH:33]=2)=[NH:26])=[NH:23])=[NH:13])=[NH:10])=[CH:6][CH:5]=[C:4]([Cl:35])[CH:3]=1.C(=O)(O)[O-].[Na+]>>[Ag+2:1].[CH:29]1[C:28]([NH:27][C:25]([NH:24][C:22]([NH:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][NH:14][C:12]([NH:11][C:9]([NH:8][C:7]2[CH:2]=[CH:3][C:4]([Cl:35])=[CH:5][CH:6]=2)=[NH:10])=[NH:13])=[NH:23])=[NH:26])=[CH:33][CH:32]=[C:31]([Cl:34])[CH:30]=1

Participants

4

Reactant 3

HCID 516892Sodium BicarbonateHCID 178419107HCID 178419107, compoundHCID 178512157Chlorohexidine

Product 1

HCID 178512158HCID 178512158, compound

Procedure

To a reaction mixture of silver (II) and chlorhexidine prepared in Step 3 of Preparation #3 was added drop wise a saturated aqueous solution of sodium bicarbonate to adjust the pH of the reaction mixture to 7.0. The reaction mixture was allowed to remain under stirring condition for at least 10 minutes and stand for at least 4 hours at room temperature to yield a brown precipitate of a microcrystalline silver (II)/polydiguanide complex.

Workup

  1. waitstand for at least 4 hours at room temperature

Sources & evidence

ORD record
ord-4dc92282b3644c8083fdcdc9d04c50c9
Source dataset
uspto-grants-2015_08
Patent number
US09108987B2

Reaction notes

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