反应详情

4-Bromobenzenecarboximidate (25 g, 0.10 mole) is added to toluene (225 ml). Then triethylamine (25 ml, 0.17 mole) is added. The reaction mixture is stirred at room temperature for 10 minutes. 4-bromobenzoyl chloride (25 g, 0.12 mole) in toluene (25 ml) is added to the reaction mixture in 30 minutes at room temperature. After stirring the reaction mixture overnight, it is filtered and the toluene layer is concentrated. The product, 4-Bromo-N-[1-(4-bromo-phenyl)-1-ethoxy-meth-(z)-ylidene]benzamide, from the toluene concentrate is then washed with methanol (30 ml) and dried in vacuum (Yield=30 g (62%)). The product is used without further purification in the next reaction step.

1. stirringAfter stirring the reaction mixture overnight, it
2. filtrationis filtered
3. concentrationthe toluene layer is concentrated
4. concentrationThe product, 4-Bromo-N-[1-(4-bromo-phenyl)-1-ethoxy-meth-(z)-ylidene]benzamide, from the toluene concentrate
5. washis then washed with methanol (30 ml)
6. customdried in vacuum (Yield=30 g (62%))
7. customThe product is used without further purification in the next reaction step