反应详情

温度

50 °C

A catalytic amount of concentrated hydrochloric acid was added to a solution of 3-(cis-4-((tert-butyldimethylsilyl)oxy)cyclohexyl)-4-cyclopentylfuran-2,5-dione (65 mg, 0.17 mmol) in ethanol (3.0 ml) at room temperature, and the mixture was stirred at 50° C. for 5 hr. The reaction mixture was allowed to cool and was then concentrated under reduced pressure. The residue was chromatographed on silica gel column (hexane:ethyl acetate=80:20) to give the title compound as a colorless solid (40 mg, yield 88%).

1. temperatureto cool
2. concentrationwas then concentrated under reduced pressure
3. customThe residue was chromatographed on silica gel column (hexane:ethyl acetate=80:20)