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HRID517140

反应详情

EQUATION

反应方程式

HRID 517140 的结构方程式

REACTANTS

反应物

2
结构：C#CC1(O)CCCCCCC1
HCID123539

Cyclooctanol, 1-ethynyl-

C10H16O

结构：O=C(NCCC(O)c1cccc(Br)c1)C(F)(F)F
HCID57608426

N-[3-(3-Bromophenyl)-3-hydroxypropyl]-2,2,2-trifluoroacetamide

C11H11BrF3NO2

PRODUCTS

生成物

1
结构：O=C(NCCC(O)c1cccc(C#CC2(O)CCCCCCC2)c1)C(F)(F)F
HCID87082498

未命名化合物

PROCEDURE

实验过程

Sonogashira reaction of 25 with 1-ethynyl-cyclooctanol yielded 2,2,2-trifluoro-N-(3-hydroxy-3-(3-(2-(1-hydroxycyclooctyl)ethynyl)phenyl)propyl)acetamide as yellow oil. Yield (0.54 g, 44%). This compound was used without further purification in the next step.