HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimedone → 5,5-Dimethyl-3-{[3-(trifluoromethyl)phenyl]amino}cyclohex-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimedone | HCID 31358 | — |
| Reactant | 6,6-Dimethyl-3-(3-(trifluoromethyl)phenylamino)cyclohex-2-enone | HCID 86732296 | — |
| Product | 5,5-Dimethyl-3-{[3-(trifluoromethyl)phenyl]amino}cyclohex-2-en-1-one | HCID 614722 | — |
Reaction Steps
The title compound is prepared in analogy to 6,6-dimethyl-3-(3-(trifluoromethyl)phenyl-amino)cyclohex-2-enone (intermediate 6), using 5,5-dimethylcyclohexane-1,3-dione (1.13 g, 8.04 mmol) as starting material. Yield: 1.73 g, ESI mass spectrum [M+H]+=284, Retention time HPLC: 1.18 min (Z005—001).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115093B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-ce18b6168b214f03bf686cd715640606 |
| Source note | uspto-grants-2015_08 |