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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 517251Generated: November 1, 2026

HCID 86732371, compound → HCID 86732372, compound

https://huagongshe.com/reaction/517251

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86732371HCID 86732371—
ReactantHCID 86732373HCID 86732373—
ProductHCID 86732372HCID 86732372—

Reaction Steps

The title compound is prepared in analogy to 2-(4-(4-cyanophenyl)-2,5-dioxo-1-(3-(tri-fluoromethyl)phenyl)-1,2,5,6,7,8-hexahydroquinazolin-3(4H)-yl)acetic acid (example 32), using (R)-methyl 2-(4-(4-cyanophenyl)-2,5-dioxo-1-(3-(trifluoromethyl)phenyl)-1,2,5,6,7,8-hexahydroquinazolin-3(4H)-yl)acetate (example 31A, 30 mg, 62 μmol) as starting material. Yield: 27 mg; ESI mass spectrum [M+H]+=470; Retention time: 1.09 min (V001—006).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115093B2
Source datasetuspto-grants-2015_08
ORD IDord-100f16e7522f411a9767d9071b4dd0c4
Source noteuspto-grants-2015_08