Pyridine → 3851-91-0

HRID 517324Notes

Reaction equation

HRID 517324 reaction equation
Cl[CH2:2][CH2:3][S:4](Cl)(=[O:6])=[O:5].[CH:8]([OH:11])([CH3:10])[CH3:9].N1C=CC=CC=1>ClCCl>[CH:8]([O:11][S:4]([CH:3]=[CH2:2])(=[O:6])=[O:5])([CH3:10])[CH3:9]

Participants

5

Reactant 3

HCID 1049PyridineHCID 3776IsopropanolHCID 15385Ethanesulfonylchloride, 2-chloro-

Product 1

HCID 122599943851-91-0

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-Chloroethylsulfonyl chloride (2 g, 12.3 mmol), isopropanol (1 mL), and pyridine (2.7 mL) were dissolved in dichloromethane (20 mL), and the mixture was stirred at room temperature for 3 hours. The reaction mixture was washed successively with 1N hydrochloric acid and water, and the organic layer was dried over anhydrous magnesium sulfate. The drying agent was filtered, and the solvent was evaporated to give the title compound (1.06 g).

Workup

  1. washThe reaction mixture was washed successively with 1N hydrochloric acid and water
  2. dry with materialthe organic layer was dried over anhydrous magnesium sulfate
  3. filtrationThe drying agent was filtered
  4. customthe solvent was evaporated

Sources & evidence

ORD record
ord-42898b2497fb41beb30ba4aee51c2e5c
Source dataset
uspto-grants-2015_08
Patent number
US09115107B2

Reaction notes

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