HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-allyl-L-aspartic acid di-tert-butyl ester hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | N-allyl-L-aspartic acid di-tert-butyl ester | HCID 86673330 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-allyl-L-aspartic acid di-tert-butyl ester hydrochloride | HCID 86673331 | 47% |
Reaction Steps
The obtained N-allyl-L-aspartic acid di-tert-butyl ester was dissolved in acetonitrile (10 mL), and water (17 mL) and 1N hydrochloric acid (1.8 mL, 1.8 mmol) were added. The solution was concentrated under reduced pressure and freeze-dried to give the title compound (0.54 g, 1.7 mmol, 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115107B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-889097096d9840028c8fd821287ab804 |
| Source note | uspto-grants-2015_08 |