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HRID517512

反应详情

EQUATION

反应方程式

HRID 517512 的结构方程式

REACTANTS

反应物

3
结构：BrCc1cccc2ccccc12
HCID137844

1-(Bromomethyl)naphthalene

C11H9Br

结构：COC(=O)[C@H](CNC(=O)c1ccc(O)cc1)N1CCN(S(C)(=O)=O)CC1
HCID67056914

未命名化合物

结构：COC(=O)[C@H](CNC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)N1CCN(S(C)(=O)=O)CC1
HCID86667909

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@H](CNC(=O)c1ccc(OCc2cccc3ccccc23)cc1)N1CCN(S(C)(=O)=O)CC1
HCID86667908

未命名化合物

PROCEDURE

实验过程

In a manner similar to example 4-5, starting from 300 mg (0.8 mmol) of methyl (S)-3-(4-hydroxybenzoylamino)-2-(4-methanesulphonylpiperazin-1-yl)-propanoate (prepared as described in example 4-4) and from 200 mg (1.2 mmol) of 1-bromomethylnaphthalene, 320 mg (78%) of methyl (S)-2-(4-methanesulphonylpiperazin-1-yl)-3-[4-(2-methylquinolin-4-ylmethoxy)benzoylamino]-propanoate are obtained in the form of a white solid.

WORKUP

后处理

  1. customare obtained in the form of a white solid