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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 517583Generated: October 30, 2026

(Z)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione → (Z)-di-tert-butyl (2-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)propane-1,3-diyl)dicarbamate

https://huagongshe.com/reaction/517583

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Z)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dioneHCID 5878179—
Reactant(Z)-tert-butyl (3-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)propyl)carbamateHCID 71697170—
ReactantDi-tert-butyl (2-bromopropane-1,3-diyl)dicarbamateHCID 86724396—
Product(Z)-di-tert-butyl (2-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)propane-1,3-diyl)dicarbamateHCID 8672439523.9%

Reaction Steps

The title compound 21e was prepared from compound 2 (292 mg, 1.17 mmol) and di-tert-butyl (2-bromopropane-1,3-diyl)dicarbamate (413 mg, 1.17 mg) in a manner similar to that described for 21a. Yield=23.9%, 130 mg.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115122B2
Source datasetuspto-grants-2015_08
ORD IDord-0a1070ca5ae749c88731f3f5a5ebb805
Source noteuspto-grants-2015_08