Sodium Hydroxide → HCID 90404447, compound

HRID 517679Notes

Reaction equation

HRID 517679 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([N:11]2[N:15]=[CH:14][CH:13]=[N:12]2)[C:5]([C:8]([O-:10])=[O:9])=[N:6][CH:7]=1.[Na+].[OH-].[Na+]>CCO>[CH3:1][C:2]1[CH:3]=[C:4]([N:11]2[N:12]=[CH:13][CH:14]=[N:15]2)[C:5]([C:8]([OH:10])=[O:9])=[N:6][CH:7]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 90404477HCID 90404477, compound

Product 1

HCID 90404447HCID 90404447, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

(sodium 5-methyl-3-(2H-1,2,3-triazol-2-yl)picolinate). To a solution of the title compound of Step A (489 mg, 2.6 mmol) in EtOH (7 mL) was added 4 N NaOH (660 μL, 2.6 mmol). The mixture was heated at 100° C. for 24 h. The reaction mixture was concentrated in vacuo to a white solid which was used without further purification in subsequent steps.

Sources & evidence

ORD record
ord-70c26e18996746aabc99ed362c39ff8f
Source dataset
uspto-grants-2015_08
Patent number
US09115117B2

Reaction notes

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