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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 517748Generated: October 31, 2026

Lithium hydroxide, monohydrate → HCID 66654364, compound

https://huagongshe.com/reaction/517748

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 66655062HCID 66655062—
SolventWaterHCID 962—
SolventTetrahydrofuranHCID 8028—
ProductHCID 66654364HCID 66654364—

Reaction Steps

To a solution of {1-[4-cyano-2-methyl-5-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl acetate (Intermediate 62, 433 mg, 1.33 mmol) in water (2 mL) and tetrahydrofuran (4 mL), cooled in an ice bath, was added lithium hydroxide monohydrate (56 mg, 1.33 mmol). The reaction was stirred at room temperature for 1 hour and 30 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115132B2
Source datasetuspto-grants-2015_08
ORD IDord-15eced4b3c6847c4ba489abe7b783762
Source noteuspto-grants-2015_08