Methyl vinyl sulfone → HCID 53330041, compound

Participants

Reaction Steps

1-Methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(trifluoromethyl)phenyl)-1H-[1,2,3]-triazolo[4,5-c]pyridine-4-carbonitrile (50 mg) and methylsulfonylethene (0.051 ml) were combined in acetonitrile (3 ml) and the reaction mixture microwaved at 120° C. for 20 minutes. The reaction mixture was concentrated under vacuum and the resulting solid suspended in methanol and filtered off to afford the title compound (43.8 mg).

Provenance & Evidence