Ethyl 2-azido-3-(5-methylthiophen-2-yl)acrylate → ethyl 2-methyl-4H-thieno[3,2-b]pyrrole-5-carboxylate

Participants

Reaction Steps

Ethyl 2-azido-3-(5-methylthiophen-2-yl)acrylate (3.38 g) was dissolved in m-xylene (30 mL) and the mixture was heated at reflux for 1 hour. The reaction solution was concentrated under reduced pressure. To the residue was added n-hexane and the residue was washed with n-hexane. The solid was collected by filtration, and dried under reduced pressure to give the title compound (2.56 g).

Provenance & Evidence