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HRID518164

反应详情

EQUATION

反应方程式

HRID 518164 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：COC(=O)/C=C/c1ccc2c(c1)C(=O)CC1(CCNCC1)O2
HCID52952093

未命名化合物

结构：COC(=O)/C=C/c1ccc2c(c1)C(=O)N(Cc1ccccc1)C1(CCN(C(=O)OC(C)(C)C)CC1)O2
HCID66932363

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)/C=C/c1ccc2c(c1)C(=O)N(Cc1ccccc1)C1(CCNCC1)O2
HCID58147954

未命名化合物

收率 97.5%

PROCEDURE

实验过程

(E)-3-{1′-Tert-butoxycarbonyl-3,4-dihydro-3-benzyl-4-oxo-spiro[2H-(1,3)-benzoxazine-2,4′-piperidin]-6-yl}-acrylic acid methyl ester (900 mg, 1.83 mmol) was deprotected with HCl according to the procedure for preparation of Intermediate 1, Step C, giving (E)-3-{3,4-dihydro-3-benzyl-4-oxo-spiro[2H-(1,3)-benzoxazine-2,4′-piperidin]-6-yl}-acrylic acid methyl ester (700 mg) as its hydrochloride salt.