反应详情

To a solution of cis-N-isopropyl-4-(5-(4-methoxybenzyloxy)-2-nitrophenylamino)cyclohexanecarboxamide (452 mg, 1.024 mmol) in MeOH (5 mL) was added AcOH (0.293 mL, 5.12 mmol) and zinc (669 mg, 10.24 mmol), and the resulting mixture was stirred at RT for 3 hours. The mixture was filtered through a pad of Celite® brand filter aid and evaporated to afford cis-4-(2-amino-5-(4-methoxybenzyloxy)phenylamino)-N-isopropylcyclohexanecarboxamide (400 mg).

1. filtrationThe mixture was filtered through a pad of Celite® brand
2. filtrationfilter aid
3. customevaporated