Acetic Acid → HCID 178491294, compound

Participants

Reaction Steps

To a solution of cis-N-isopropyl-4-(5-(4-methoxybenzyloxy)-2-nitrophenylamino)cyclohexanecarboxamide (452 mg, 1.024 mmol) in MeOH (5 mL) was added AcOH (0.293 mL, 5.12 mmol) and zinc (669 mg, 10.24 mmol), and the resulting mixture was stirred at RT for 3 hours. The mixture was filtered through a pad of Celite® brand filter aid and evaporated to afford cis-4-(2-amino-5-(4-methoxybenzyloxy)phenylamino)-N-isopropylcyclohexanecarboxamide (400 mg).

Provenance & Evidence